Prosthesis and Orthopedy
Ostim is a nanocrystalline paste of calcium hydroxyapatite (HA) [Ca10(PO4)6(OH)2] with crystals of 20 nm diameter approved by the FDA through the 510(k) process in 2004. The structure of HA resembles natural bone minerals with the ability for osteoconduction. Osteoconduction is the ability of bone to grow on a surface, thereby providing Ostim with good biocompatibility. As a bone-grafting material, Ostim can be used in orthopedic and dental surgery procedures. The process of commercially preparation includes rapid precipitations to produce a paste containing 25% water with dispersed nano-sized needle shaped HA crystals.