NanoTherm® therapy is a new approach to the local treatment of solid tumors. The method is based on the principle of introducing magnetic nanoparticles directly into a tumor and then heating them in an alternating magnetic field. At approximately 15 nanometers in diameter, the nanoparticles, which are suspended in water, are extremely small (a nanometer is one millionth of a millimeter), and comprise an iron oxide core with an aminosilane coating. The particles are activated by a magnetic field that changes its polarity up to 100,000 times per second, generating heat.Depending on the duration of treatment and the temperatures achieved within the tumor, the tumor cells are either irreparably damaged or sensitized for additional chemo- or radiotherapy.With this new procedure, it is possible to combat the tumor from within, while sparing surrounding healthy tissue. Thanks to their coating, the nanoparticles remain at the treatment site, allowing repeated treatments and multimodal therapy concepts.