|Zist Abzar Pajoohan|
Medicine Medical SuppliesDetection Kit
The rapid drug detection kit operates in a competitive assay. The cut off for each country varies according to the laws of that country. Test results can be checked quickly after 3 minutes. These types of kits are heavily sensitive to moisture The cut off for each drug is as follows: Gold nanoparticles were used in this kit, and antibodies are attached to these gold nanoparticles for drug detection. If only the control line is switched on, the test will be performed correctly and the result of the presence of the drug will be positive. If both control and test lines are switched on, the test will be performed correctly and the result of the presence of the drug will be negative. If the test control line is switched off, the test will not be performed correctly.
Nowadays, a rapid test for detection and control of drugs has been developed by immuno-chromatography methods. Lateral flow assay is one of the common methods.
The LFA detection kit is divided into two categories:
The rapid drug detection kit operates in a competitive assay.
In order to make this kind of kit on its release pads, gold nanoparticles are attached to the antibody of drug detection. This antibody is for limited concentration. By applying the analyte containing the drug onto the sample pad and passing it on the release pad, the nanoparticles attached to the antibody are attached to the sample drug. Some drugs are placed on the test line and antibody is placed on the control line. With the arrival of nanoparticles attached to the antibody to this line, its color will be light and consequently the test will be correct. The structure of the competitive detection type kit is as follows: