SLINTEC RT-LAMP kit

While under the current PCR regime, it usually takes around 3-4 hours to receive test results in a lab, SLINTEC’s RT-LAMP-based test kit only requires around 30 minutes. It has also shown added benefits such as higher sensitivity and specificity.

nitially, SLINTEC RT-LAMP kit was validated against the existing RT-qPCR test at the University of Sri Jayawardenapura using over 300 clinical samples in August last year. Further, it was also independently validated by NMRA by testing them at MRI, IDH and Karapitiya hospital PCR laboratories.

According to Jayaweera, results of the initial trial conducted with RT-LAMP test kits perfectly matched with the results of RT-qPCR test, which was later again independently validated by NMRA by testing them at MRI, IDH and Karapitiya hospital PCR laboratories.

“In fact, RT-LAMP shows much better sensitivity than PCR. This is going to become the gold standard moving forward,” he stressed.

In addition to the ability to deliver quicker results, the country is also expected to decrease total reagent cost by three-fold with a potential four-fold increase in pipeline output by switching to RT-LAMP-based COVID test kits.

SLINTEC has predicted that Sri Lanka could save Rs. 150 million per month spent on COVID-19 testing.

Jayaweera hopes a test-kit to be priced below Rs.1000 in the market, the price of one third of a traditional PCR test kit. 

“The final shelf price will depend on several factors in addition to output cost, the other costs-related to marketing, and distribution needs to be added up to determine the final price,” he said.

Although, Antigen test kits are priced below the traditional PCR test kits, he pointed out that Antigen tests have only 60 percent effectiveness in identifying the virus.

SLINTEC is currently in negotiation with two private sector firms to commence commercial production.

“Up to now, we have invested our own funds. However, we are looking at a private-sector partner in the pharmaceutical sector for the production and to set standards for continuous production. We are already in negotiation with two parties and hope to finalise it very soon,” Jayaweera noted.

Meanwhile, SLINTEC is also moving ahead with research to introduce RT-LAMP-based home test-kits using saliva. 

“We are also working on developing home-test kits by using saliva. It’s still at the research stage. Initial test results are promising, but we can’t say much as it still in the research stage. The ultimate goal is to develop a test kit that is based on saliva and can get tested at your own home,” Jayaweera revealed.