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Registration Date 3 Jun 2021
Revision Date 3 Jun 2021
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PLGA-PEI nanoparticles

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Construction Masonry Materials

Poly(lactic-co-glycolic acid) PLGA Nanoparticles

Applications

Gene Delivery Gene Therapy

Properties

Available in different sizes: 100 nm or 200 nm Amphiphilic: both hydrophilic and lipophilic compounds can be encapsulated Optional fluorescence: non- fluorescent, green fluorescent (EX/EM 498 nm/517 nm), red fluorescent (EX/EM 525 nm/548 nm) Biodegradability, biocompatibility and controlled release High efficiency for gene transfection and gene delivery

Biodegradability Biocompatibility Amphiphilic Controlled release of active agents High efficiency for gene transfection High efficiency for gene delivery Optional fluorescence

Manufacturer's Description

Creative Diagnostics provides biodegradable poly (d,l-lactide-co-glycolide) (PLGA) nanoparticles bearing polyethyleneimine (PEI) on their surface, DiagPoly™ PEI PLGA Nanoparticles, which is based on poly(lactide-co-glycolide) (PLGA) acid terminated with a lactide/glycolide ratio of 50/50 and a molecular weight of 32000 Da. These nanoparticles are positively charged due to the surface modification with PEI. PLGA-PEI nanoparticles are recommended for gene delivery and gene therapy.