PLGA-PEI nanoparticles

Available in different sizes: 100 nm or 200 nm Amphiphilic: both hydrophilic and lipophilic compounds can be encapsulated Optional fluorescence: non- fluorescent, green fluorescent (EX/EM 498 nm/517 nm), red fluorescent (EX/EM 525 nm/548 nm) Biodegradability, biocompatibility and controlled release High efficiency for gene transfection and gene delivery

Creative Diagnostics provides biodegradable poly (d,l-lactide-co-glycolide) (PLGA) nanoparticles bearing polyethyleneimine (PEI) on their surface, DiagPoly™ PEI PLGA Nanoparticles, which is based on poly(lactide-co-glycolide) (PLGA) acid terminated with a lactide/glycolide ratio of 50/50 and a molecular weight of 32000 Da. These nanoparticles are positively charged due to the surface modification with PEI. PLGA-PEI nanoparticles are recommended for gene delivery and gene therapy.