Saphyr Chip®

Built using proprietary Nanochannel technology, Bionano Chips for the Saphyr® and Irys® systems linearize DNA, enabling high-speed, high-throughput optical genome mapping and structural variation detection for a variety of applications including human and clinical research.

The Bionano Saphyr Chip® and Irys Chip® utilize hundreds of thousands of massively parallel NanoChannels per flow cell that linearize long DNA molecules allowing Bionano systems to directly image your samples.

Inside the chip’s flow cell, a gradient of micro- and nano-structures, upstream of the chip’s NanoChannels, gently unwinds and guides DNA into the NanoChannels. Saphyr Chip’s NanoChannels allow only a single linearized DNA molecule to travel through while preventing the molecule from tangling or folding back on itself.

By leveraging mature semiconductor manufacturing technology, Bionano delivers robust performance and quality. The breakthrough Saphyr Chip combines with the Bionano Direct Label and Staining (DLS) technology to provide you with the highest sensitivity possible for structural variant detection starting at 500 bp, along with genome maps up to chromosome-arm-length.